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K Hirose Selected Research

Reactive Oxygen Species (Oxygen Radicals)

6/2006Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells.
5/2000Nerve growth factor-induced neuronal differentiation requires generation of Rac1-regulated reactive oxygen species.

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K Hirose Research Topics

Disease

9Neoplasms (Cancer)
06/2011 - 04/2000
5Infections
05/2004 - 01/2001
4Leukemia
03/2013 - 09/2000
4Breast Neoplasms (Breast Cancer)
07/2005 - 01/2001
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
03/2013 - 02/2007
3Carcinoma (Carcinomatosis)
04/2010 - 04/2000
2Lung Neoplasms (Lung Cancer)
01/2021 - 05/2001
2Pain (Aches)
07/2016 - 04/2001
2Osteoarthritis
07/2016 - 04/2001
2Pathologic Constriction (Stenosis)
07/2003 - 12/2000
2Colorectal Neoplasms (Colorectal Cancer)
04/2003 - 04/2000
2Myotonic Dystrophy (Dystrophia Myotonica)
12/2001 - 05/2000
2Stomach Neoplasms (Stomach Cancer)
11/2000 - 10/2000
1Hypoxia (Hypoxemia)
01/2021
1Psoriasis (Pustulosis Palmaris et Plantaris)
01/2018
1Asthma (Bronchial Asthma)
07/2017
1Metaplasia
07/2017
1Alzheimer Disease (Alzheimer's Disease)
01/2017
1Atherosclerosis
01/2017
1Hearing Loss (Hearing Impairment)
01/2017
1Type C Niemann-Pick Disease (Niemann Pick Disease, Type C)
01/2017
1Chronic Pain
07/2016
1Low Back Pain (Lumbago)
07/2016
1Neuralgia (Stump Neuralgia)
07/2016
1Peripheral Nervous System Diseases (PNS Diseases)
07/2016
1Surgical Wound Infection
02/2014
1Cardiac Arrhythmias (Arrythmia)
02/2014
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
03/2013
1Philadelphia Chromosome
03/2013
1Neuroblastoma
06/2011
1Carcinogenesis
04/2010
1Myeloid Leukemia (Leukemia, Myelocytic)
10/2008
1Colonic Neoplasms (Colon Cancer)
08/2008
1Renal Insufficiency (Renal Failure)
02/2007
1Hypercalcemia (Milk Alkali Syndrome)
02/2007
1Pancreatic Neoplasms (Pancreatic Cancer)
06/2006
1Atlanto-Axial Fusion
07/2005

Drug/Important Bio-Agent (IBA)

6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2013 - 08/2000
4CytokinesIBA
10/2001 - 08/2000
3InterleukinsIBA
01/2018 - 09/2000
3LigandsIBA
03/2013 - 12/2006
3Death Domain ReceptorsIBA
03/2013 - 12/2006
2ORALIT (ORS)IBA
04/2010 - 05/2001
2DNA (Deoxyribonucleic Acid)IBA
10/2008 - 08/2008
2Proteins (Proteins, Gene)FDA Link
08/2008 - 07/2001
2Reactive Oxygen Species (Oxygen Radicals)IBA
06/2006 - 05/2000
2Messenger RNA (mRNA)IBA
06/2006 - 11/2000
25-HT2A Serotonin Receptor (5 HT2A Receptor)IBA
12/2001 - 04/2000
2N- (2- (4- (5H- dibenzo(a,d)cyclohepten- 5- yliden)piperidino)ethyl)- 1- formyl- 4- piperidinecarboxamide (AT 1015)IBA
12/2001 - 04/2000
2Levofloxacin (Levaquin)FDA Link
10/2001 - 04/2001
2Interleukin-15 (Interleukin 15)IBA
07/2001 - 01/2001
2Complementary DNA (cDNA)IBA
07/2001 - 09/2000
2TeaIBA
06/2001 - 04/2001
2Progesterone Receptors (Progesterone Receptor)IBA
06/2001 - 01/2001
2Estrogens (Estrogen)FDA Link
06/2001 - 01/2001
2Indicators and Reagents (Reagents)IBA
11/2000 - 05/2000
2Telomerase (Telomerase Reverse Transcriptase)IBA
10/2000 - 04/2000
1VimentinIBA
01/2021
1Cadherins (E-Cadherin)IBA
01/2021
1Hypoxia-Inducible Factor 1IBA
01/2021
1Monoclonal AntibodiesIBA
01/2018
1guselkumabIBA
01/2018
1AllergensIBA
07/2017
1MucinsIBA
07/2017
1Pattern Recognition ReceptorsIBA
07/2017
12-Hydroxypropyl-beta-cyclodextrinIBA
01/2017
1TapentadolFDA Link
07/2016
1NAD (NADH)IBA
07/2016
1ElectrolytesIBA
02/2014
1CatecholaminesIBA
02/2014
1Glucose (Dextrose)FDA LinkGeneric
02/2014
1nilotinibFDA Link
03/2013
1TNF-Related Apoptosis-Inducing LigandIBA
03/2013
1Imatinib Mesylate (Gleevec)FDA Link
03/2013
1Dasatinib (BMS 354825)FDA Link
03/2013
1Tyrosine Kinase InhibitorsIBA
03/2013
1Small Interfering RNA (siRNA)IBA
03/2013
1Vitamin DFDA LinkGeneric
04/2010
1Dietary CalciumIBA
04/2010
1CalciumIBA
04/2010
1nuclear pore complex protein 98IBA
10/2008
1Diphosphonates (Bisphosphonates)IBA
02/2007
1Parathyroid Hormone-Related ProteinIBA
02/2007
1diphenyleneiodoniumIBA
06/2006
1Superoxides (Superoxide)IBA
06/2006
1MAP Kinase Kinase Kinase 5IBA
06/2006
1NADPH Oxidase 4IBA
06/2006
1NADPH Oxidases (NAD(P)H oxidase)IBA
06/2006
1FlavoproteinsIBA
06/2006
1IsoflavonesIBA
07/2005
1thymoglobulinFDA Link
05/2004
1SteroidsIBA
05/2004

Therapy/Procedure

2Stem Cell Transplantation
03/2013 - 12/2012
2Catheters
07/2003 - 08/2000
1Aftercare (After-Treatment)
01/2017
1Critical Care (Surgical Intensive Care)
02/2014
1Therapeutics
03/2013
1Transplantation
06/2011
1Hematopoietic Stem Cell Transplantation
12/2006
1Conservative Treatment
07/2005